Publications

Aerosolized BC-819 inhibits primary but not secondary lung cancer growth, PLoS One. 2011;6(6):e20760. Epub 2011 Jun 8. Hasenpusch G, Pfeifer C, Aneja MK, Wagner K, Reinhardt D, Gilon M, Ohana P, Hochberg A, Rudolph C.

Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of IGF2-P3 and IGF2-P4 regulatory sequences, Int J Clin Exp Med. 2011;4(2):91-102. Epub 2011 Apr 30. Amit D, Tamir S, Birman T, Gofrit ON, Hochberg A.

Suicide activation in a 5-fluorouracil resistant colon cancer model in vitro, Int J Clin Pharmacol Ther. 2011 Jan;49(1):69-70. Mader RM, Kalipciyan M, Ohana P, Hochberg A, Steger GG.

Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences, J Transl Med. 2010 Dec 16;8:134. Amit D and Hochberg A.

Targeting diphtheria toxin and TNF alpha expression in ovarian tumors using the H19 regulatory sequences, Int J Clin Exp Med. 2010 Sep 21;3(4):270-82. Mizrahi A, Hochberg A, Amiur S, Gallula J, Matouk I, Birman T, Levy T, Ladimir S, Ohana P.

Use of H19 Gene Regulatory Sequences in DNA-Based Therapy for Pancreatic Cancer, J Oncol. 2010;2010:178174. Epub 2010 Oct 28. Scaiewicz V, Sorin V, Fellig Y, Birman T, Mizrahi A, Galula J, Abu-Lail R, Shneider T, Ohana P, Buscail L, Hochberg A, Czerniak A.

Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report. J Med Case Reports. 2010 Jul 27;4:228. Mizrahi A, Czerniak A, Ohana P, Amiur S, Gallula J, Matouk I, Abu-Lail R, Birman T, Hochberg A, Levy T.

The oncofetal H19 RNA connection: Hypoxia, p53 and cancer, BioChimica et Biophysica Acta (BBA) - Molecular Cell Research, 1803(4):443-451. Epub 2010. I. Matouk, S. Mezan, A. Mizrahi, P. Ohana, R. Abu-lail, Y. Fellig, N. deGroot, E. Galun andA. Hochberg.

Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences, Journal of Translational Medicine, Vol. 7, 69-79, 2009. A. Mizrahi, A. Czerniak, T. Levy, S. Amiur, J. Gallula, I. Matouk, R. Abu-lail, V. Sorin, T. Birman, N. de Groot, A Hochberg and P. Ohana.

Phase I/II Marker Lesion Study of Intravesical BC-819 DNA Plasmid in H19 Over Expressing Superficial Bladder Cancer Refractory toBacillus Calmette-Guerin, The Journal of Urology, Vol. 180, 2379-2383, 2008. A. A. Sidi, P. Ohana, S. Benjamin, M. Shalev, J. H. Ransom, D. Lamm, A. Hochberg and I. Leibovitch

The H19 Non-Coding RNA is Essential for Human Tumor Growth, PLoS ONE 2:e845, 2007. I.J. Matouk, N. DeGroot, S. Mezan, S.Ayesh, R. Abu-lail, A. Hochberg and E. Galun.

A Non-invasive QPCR Method Monitoring DNA Based Therapy of Bladder Cancer Patients, Vaccine 24:34203425, 2006. S. Ayesh, R. Abu-Lail and A. Hochberg.

The Oncofetal H19 RNA in human cancer, from the bench to the patient, Cancer Therapy Vol 3, Page 1, 2005. I. Matouk, P. Ohana, S. Ayesh, A. Sidi, A. Czerniak N. de Groot, and A. Hochberg.

Regulatory sequences of the H19 gene in DNA based therapy of bladder cancer, Gene Therapy & Molecular Biology, Vol. 8, 181-192, 2004. P. Ohana, O. Gofrit, S. Ayesh, W. Al-Sharef, A. Mizrahi, T. Birman, T. Schneider, I. Matouk, N. de Groot, E. Tavdy, A. Sidi and A. Hochberg.

Regulatory Sequences of H19 and IGF2 Genes in DNA-Based Therapy of Colorectal Rat Liver Metastases, Journal of Genetic Medicine, 2004 Nov 1. P. Ohana, P. Schachter, B. Ayesh, A. Mizrahi, T .Birman, T. Schneider, I. Matouk, S. Ayesh, P.J. Kuppen, N. de Groot, A. Czerniak and A. Hochberg.

The involvement of H19 non-coding RNA in Stress: Implications in cancer development and prognosis, Gene Therapy & Molecular Biology, Vol. 8, 403-412, 2004. S. Ayesh, I. Farreh, T. Schneider, N. de Groot and A. Hochberg.